The respiratory system
By the end of this topic you'll know what ventilation is, the path air takes into the lungs, and how the trachea is built to stay open and stay clean.
Part 1What is the respiratory system?
You breathe about 20 000 times a day, usually without thinking about it. Each breath, air travels from your nose all the way down to tiny sacs deep in your lungs. The job of this whole system is ventilation — the movement of air (gases) INTO and OUT OF the lungs.
Why do you do it? You breathe IN to take in oxygen, which your body needs. You breathe OUT to get rid of carbon dioxide, a waste gas. Air does not jump straight to your lungs — it follows a clear pathway, getting into smaller and smaller tubes.
nose → trachea → bronchi → bronchioles → alveoli
The trachea is your windpipe — the main tube. It branches into two bronchi (one per lung), which split into tiny bronchioles, which end in the alveoli (the air sacs where gases are swapped). Around all this, your ribs protect the lungs, and the diaphragm (a sheet of muscle) sits below them.
Keywords for Part 1
- Ventilation
- ventilare = "to fan / make a wind." The movement of air (gases) into and out of the lungs.
- Respiratory
- respirare = "to breathe again." To do with breathing — the system that moves air in and out.
- Trachea
- trakheia = "rough." The windpipe — the tube carrying air to the lungs.
What is the correct path of air into the lungs?
- Anose → bronchi → trachea → alveoli
- Bnose → trachea → bronchi → bronchioles → alveoli
- Cnose → alveoli → bronchi → trachea
- Dtrachea → nose → lungs
Show answer
Part 2The trachea is built for the job
Press gently on the front of your throat and you can feel hard rings under the skin. Those are rings of cartilage. They hold the trachea OPEN so it cannot collapse under pressure when you breathe — like the rings in a vacuum-cleaner hose.
The inside of the trachea also keeps itself clean. It is lined with two kinds of cell. Goblet cells release sticky mucus that traps dust and germs. Ciliated epithelial cells are covered in cilia — tiny hairs that sweep the dirty mucus UP and OUT towards your throat, where it is swallowed or coughed away. ('Epithelial' just means a surface cell.)
So the two work as a team: mucus traps the dirt, and cilia sweep it away — keeping the airway clean.
Keywords for Part 2
- Cartilage
- Tough, flexible tissue. Forms rings that hold the trachea open.
- Cilia
- Tiny hairs on the cells lining the trachea. They sweep mucus (with trapped dust and germs) up and out.
- Goblet cells
- Cells that release the sticky mucus which traps dust and germs.
⚠ Watch out — "we only breathe in oxygen"
A common mistake. The air you breathe in is a mixture — mostly nitrogen (about 78%), plus oxygen (about 21%) and a few others. Oxygen is the gas your body actually uses, but it is not the only gas you take in.
What is the job of the cilia in the trachea?
- Ato make mucus
- Bto sweep mucus, dust and germs up and out
- Cto hold the trachea open
- Dto exchange gases
Show answer
Test yourself
7 questions · click to reveal each answer
What is ventilation?
The movement of air (gases) into and out of the lungs.List, in order, the parts air passes through into the lungs.
Nose → trachea → bronchi → bronchioles → alveoli.What is the function of the cartilage rings in the trachea?
To hold the trachea open so it does not collapse under pressure.Name the two types of cell that line the trachea.
Ciliated epithelial cells and goblet cells.How do the cells lining the trachea work together to remove dust and bacteria?
Goblet cells make mucus that traps dust and germs; cilia sweep the mucus up and out. Together they keep the airway clean.A student says "we only breathe in oxygen." Why are they wrong?
We breathe in a mixture — mostly nitrogen (~78%), plus oxygen (~21%) and other gases. Oxygen is just the gas we use.STRETCH: Suggest why a smoker, whose cilia are damaged, gets a "smoker's cough."
With the cilia damaged, mucus is not swept away, so it builds up — the body coughs to try to clear it.
How do the lungs work?
By the end of this topic you'll be able to explain how changing the volume of your chest changes the pressure inside — and how that makes air rush in and get forced out.
Part 1The lungs can't move themselves
Here is the surprise: your lungs have no muscles of their own. They cannot pull air in by themselves. So what makes air rush IN when you breathe in? The answer is a change in volume and pressure, driven by two sets of muscles around the lungs.
Those two muscles are the intercostal muscles (between the ribs) and the diaphragm (the sheet of muscle under the lungs). When they move, they change the size of the chest — and that changes everything.
The key rule to lock in: a bigger space holds gas at a LOWER pressure; a smaller space holds gas at a HIGHER pressure. And air always flows from HIGH pressure to LOW pressure.
Keywords for Part 1
- Intercostal muscles
- The muscles between the ribs. They move the ribcage up/out or down/in.
- Diaphragm
- A large flat sheet of muscle below the lungs. It flattens down or domes up to change the chest volume.
- Pressure
- How hard the air pushes. In a bigger space the same air is more spread out, so the pressure is lower.
Part 2Breathing IN and breathing OUT
When you breathe IN: the intercostal muscles and diaphragm CONTRACT. The ribcage moves UP and OUT, and the diaphragm flattens DOWN. This makes the chest volume INCREASE. A bigger volume means the pressure inside DROPS — below the pressure outside. So air rushes IN, from high pressure outside to low pressure inside.
When you breathe OUT: the same muscles RELAX. The ribcage drops down and in, and the diaphragm domes back up. The chest volume DECREASES, so the pressure inside RISES — above the pressure outside. So air is forced OUT.
It is the change in chest VOLUME that changes the PRESSURE — and the difference in pressure is what moves the air.
⚠ Watch out — the lungs have no muscles of their own
It is tempting to say "the lungs pull the air in." They don't — they can't. It is the diaphragm and intercostal muscles that move, changing the chest volume. The lungs just follow the pressure change. A bell-jar model shows this well, but remember it's only a model — it has no intercostal muscles, the ribcage doesn't move, and it shows no gas exchange.
When we breathe IN, what does the diaphragm do?
- Arelaxes and moves up
- Bcontracts and flattens (moves down)
- Cstays still
- Dmakes mucus
Show answer
Why does air rush into the lungs when we breathe in?
- Athe lungs pull it in with muscles
- Bthe chest volume increases, lowering the pressure inside
- Cthe pressure inside rises
- Dthe diaphragm relaxes
Show answer
Test yourself
7 questions · click to reveal each answer
What happens to the diaphragm when we inhale?
It contracts and flattens (moves down).What happens to the intercostal muscles when we inhale?
They contract, pulling the ribcage up and out.What happens to chest volume and pressure when we inhale?
Volume increases; pressure inside drops (below the outside pressure).What happens to the diaphragm, volume and pressure when we exhale?
The diaphragm relaxes and domes up; volume decreases; pressure rises — so air is forced out.In a bell-jar model, what do the rubber sheet, the balloons and the jar represent?
Rubber sheet = the diaphragm; balloons = the lungs; jar = the ribcage.When do the lungs have higher pressure: inhaling or exhaling?
Exhaling — smaller volume means higher pressure, which forces air out.STRETCH: Explain, step by step, why air is forced out when we exhale.
Muscles relax → chest volume falls → pressure inside rises above the outside pressure → air is pushed out.
Inhaled & exhaled air
By the end of this topic you'll know exactly what changes — and what doesn't — between the air you breathe in and the air you breathe out.
Part 1What's actually in a breath
People often say "we breathe in oxygen and breathe out carbon dioxide." That's a neat story, but it isn't quite right. Most of every breath — IN and OUT — is a gas your body never uses at all: nitrogen, about 78%. It goes in and comes straight back out, unchanged.
Only two gases change much between inhaled and exhaled air:
Oxygen FALLS from about 21% to about 16%. You only use about 5% of each breath's oxygen — but that's enough to live on. Carbon dioxide RISES from about 0.04% to about 4% — that's roughly 1000 times more than you breathed in. You also breathe out more water vapour than you breathe in (which is why your breath mists a cold mirror).
The four gases to remember
- Nitrogen — 78% → 78%
- The most common gas. Your body does not use it, so it stays the same in and out.
- Oxygen — 21% → 16%
- Falls by about 5%, the part your body uses each breath. Plenty is still breathed back out.
- Carbon dioxide — 0.04% → 4%
- Rises about 1000 times. It is the waste gas your body removes.
- Water vapour — a little → more
- You breathe out more water vapour than you breathe in.
Part 2Why the air changes
Why is there LESS oxygen in exhaled air? Because about 5% of the oxygen has diffused into your blood to be used by your cells. Why is there MORE carbon dioxide? Because your body makes CO2 as a waste product, and it is breathed out. The nitrogen doesn't change because your body never touches it.
This is why exhaled air is still good enough for the "kiss of life" — rescue breaths. It still contains about 16% oxygen, which is enough to keep another person's cells supplied.
⚠ Watch out — exhaled air still has ~16% oxygen
It is wrong to think you "take in all the oxygen you inhale." You only use about 5% — so roughly 16% oxygen is still there in the air you breathe out. That leftover oxygen is exactly why rescue breaths work.
Which gas makes up the highest percentage of the air we breathe?
- Aoxygen
- Bcarbon dioxide
- Cnitrogen
- Dwater vapour
Show answer
Why is there LESS oxygen in exhaled air than inhaled air?
- Athe body destroys oxygen
- Bsome oxygen has diffused into the blood to be used
- Coxygen turns into nitrogen
- Dwe breathe out only carbon dioxide
Show answer
Test yourself
8 questions · click to reveal each answer
What percentage of inhaled air is oxygen? What about exhaled air?
Inhaled: about 21%. Exhaled: about 16%.What percentage of air (in AND out) is nitrogen?
About 78%, unchanged.What percentage of exhaled air is carbon dioxide?
About 4% (up from about 0.04% inhaled).Give two differences and one similarity between inhaled and exhaled air.
Differences: oxygen falls (21%→16%); carbon dioxide rises (0.04%→4%) (also more water vapour out). Similarity: nitrogen is the same (78%).Why does exhaled air still contain a lot of oxygen?
We only use about 5% of each breath's oxygen, so ~16% is still breathed back out.Why is exhaled air good enough for the "kiss of life"?
It still contains about 16% oxygen — enough for another person's cells to use.Do we breathe out more or less water vapour than we breathe in? How could you prove the CO2 change?
More water vapour. To prove the extra CO2, bubble exhaled air through limewater — it turns cloudy faster than room air does.STRETCH: By roughly how many times does carbon dioxide increase from inhaled to exhaled air?
About 1000 times (from 0.04% to 4%).
How does gas exchange happen?
By the end of this topic you'll be able to explain how oxygen and carbon dioxide swap over in the alveoli — by diffusion, and without using any energy.
Part 1The swap in the alveoli
The air you breathe IN is rich in oxygen but low in carbon dioxide. The blood arriving at your lungs is the opposite: low in oxygen, high in carbon dioxide. In the tiny air sacs — the alveoli — the two swap over.
Each alveolus is wrapped in tiny blood vessels called capillaries. Here is the rule:
Oxygen is HIGH in the alveolus and LOW in the blood, so oxygen diffuses INTO the blood. Carbon dioxide is HIGH in the blood and LOW in the alveolus, so carbon dioxide diffuses OUT OF the blood, into the alveolus, to be breathed out.
Both gases move by diffusion — the net movement of particles from a HIGH to a LOW concentration. And diffusion is passive: it needs NO energy.
Keywords for Part 1
- Diffusion
- The net (overall) movement of particles from a HIGH to a LOW concentration. It needs no energy.
- Alveoli
- The tiny air sacs in the lungs where gas exchange happens (one is an alveolus).
- Capillary
- A tiny blood vessel. A network of them wraps around each alveolus.
- Concentration
- How much of a gas there is in a space. Diffusion always runs from high to low concentration.
⚠ Watch out — not every gas "diffuses into the blood"
A student might say "all the gases we inhale diffuse into our blood." Not so. Only oxygen diffuses across in useful amounts. The nitrogen and other gases are mostly just breathed back out. And the gases move by diffusion — not by "breathing," not by active transport, and not by osmosis (osmosis is for water).
Which gas diffuses FROM the alveolus INTO the blood?
- Acarbon dioxide
- Boxygen
- Cnitrogen
- Dwater vapour
Show answer
By what process do oxygen and carbon dioxide move in the lungs?
- Aactive transport
- Bosmosis
- Cdiffusion
- Dbreathing
Show answer
Part 2Writing the 6-mark answer
A common exam question asks you to explain the whole swap using concentration and diffusion. Here is a full-mark answer, with each (1) showing where a mark is earned.
6-mark model answer
Explain how oxygen gets from the air in an alveolus into the blood, and how carbon dioxide is removed. Use the idea of concentration and diffusion. [6 marks]
⚠ Mark-scheme note
One mark each for: alveoli + capillaries; oxygen higher in the alveolus; oxygen diffuses into the blood; carbon dioxide higher in the blood; carbon dioxide diffuses into the alveolus; both move by diffusion. Maximum 6 marks. The examiner wants the direction AND the reason (the concentration difference) every time — never just "oxygen goes in."
Test yourself
8 questions · click to reveal each answer
Where does gas exchange happen, and what surrounds each alveolus?
In the alveoli of the lungs; each one is surrounded by a network of capillaries (blood).Which gas diffuses into the blood, and which diffuses out of the blood?
Oxygen diffuses into the blood; carbon dioxide diffuses out of the blood.Why does oxygen diffuse INTO the blood?
Oxygen is at a higher concentration in the alveolus than in the blood, so it diffuses from high to low.Why does carbon dioxide diffuse INTO the alveolus?
Carbon dioxide is at a higher concentration in the blood than in the alveolus, so it diffuses out of the blood.Does gas exchange use energy? Explain.
No — it happens by diffusion, which is passive (high to low concentration, no energy needed).What is diffusion?
The net movement of particles from a high to a low concentration.Where does the oxygen go after it enters the blood?
It is carried in the blood to the body cells to be used. (At the cells, oxygen diffuses out of the blood, because the cells are low in oxygen.)STRETCH: Why does keeping the blood flowing help gas exchange continue?
Flowing blood carries the oxygen away, keeping its concentration in the capillary low — so the difference stays big and oxygen keeps diffusing in.
Adaptations of the alveoli
By the end of this topic you'll know the four features that make the alveoli brilliant at their job — and exactly how each one speeds up diffusion.
Part 1Four features, one goal: FASTER diffusion
An adult has around 300 million tiny alveoli. Spread flat, they would cover about half a tennis court. Their walls are just one cell thick, and they are always kept moist. Why does that matter? Because every one of these features makes diffusion FASTER. Here are the four to learn:
1. Large surface area. Millions of folded alveoli give a huge area, so more gas can diffuse across at once.
2. Thin walls (one cell thick). The alveolus and capillary walls are one cell thick, giving a SHORT diffusion pathway — gases cross quickly.
3. Good blood supply. A network of capillaries carries gases away, keeping the concentration difference BIG so diffusion keeps going.
4. Moist surface. Gases dissolve in the moisture and diffuse faster.
Keywords for Part 1
- Surface area
- The total area available for diffusion. Bigger = more gas crosses at once.
- Diffusion pathway
- The distance a gas has to travel. Thin walls give a short pathway, so diffusion is fast.
- Concentration difference
- The gap in concentration between two places (also called the gradient). A bigger gap = faster diffusion.
Why are the alveoli walls only one cell thick?
- Ato store more air
- Bto give a short diffusion pathway so gases cross quickly
- Cto make mucus
- Dto hold the lungs open
Show answer
How does a good blood supply help gas exchange?
- Ait warms the air
- Bit keeps the concentration difference big so diffusion continues
- Cit makes the walls thicker
- Dit removes mucus
Show answer
Part 2Writing the 6-mark answer
This is a classic exam question. Name at least three adaptations and link each one to faster diffusion. Here's the full-mark version with each (1) marked.
6-mark model answer
Explain how the alveoli are adapted to allow efficient gas exchange. Give at least three adaptations and link each to faster diffusion. [6 marks]
⚠ Mark-scheme note
One mark each for: large surface area (millions/folded); thin walls = short pathway; good blood supply = keeps the gradient; moist surface; linking features to faster diffusion; overall efficiency. Maximum 6 marks. Naming a feature is only half a mark's worth — you must say what it does and link it to diffusion.
Test yourself
7 questions · click to reveal each answer
Name four adaptations of the alveoli.
Large surface area, thin walls (one cell thick), good blood supply, moist surface.How does a large surface area help?
It gives more room for gases to diffuse across at once.How do thin walls help?
They give a short diffusion pathway, so gases cross quickly.How does a moist surface help?
Gases dissolve in the moisture and diffuse faster.Roughly how many alveoli does an adult have, and what gives the big surface area?
About 300 million. The surface area comes from millions of tiny, highly folded sacs.Name three factors that affect the rate of gas exchange.
Surface area, diffusion distance (wall thickness), and concentration difference.STRETCH: Why are the alveoli and the small intestine's villi adapted in similar ways?
Both are exchange surfaces, so both have a large, thin, moist, well-supplied surface to absorb substances quickly.
Exercise & asthma
By the end of this topic you'll know why exercise makes you breathe faster, and what goes wrong with the airways in asthma.
Part 1Why exercise speeds up breathing
After a sprint you pant hard for a minute or two, then your breathing settles. Why? During exercise your muscles work harder, so they need much more oxygen. They also produce much more carbon dioxide as waste. To cope, your breathing rate RISES — you breathe faster and deeper to take in oxygen and remove the extra CO2.
When you stop, your breathing stays fast for a while, until the extra carbon dioxide has been cleared out. A fitter person's breathing rate returns to normal more quickly afterwards — so a recovery graph can tell you who is fitter. (And when you're asleep, with your muscles resting, your breathing rate is LOWER than at rest.)
Keywords for Part 1
- Breathing rate
- How many breaths you take per minute. It rises with exercise and falls during sleep.
- Recovery
- The time taken for breathing to return to normal after exercise. Shorter recovery = fitter.
Why does breathing rate increase during exercise?
- Ato cool the body down
- Bto take in more oxygen and remove more carbon dioxide
- Cto make more mucus
- Dto slow the heart
Show answer
Part 2What asthma does to the airways
Someone having an asthma attack can struggle to breathe even sitting still. Asthma is a condition where the lining of the airways becomes irritated and inflamed. Three things then happen at once: the muscles around the airways contract (tightening them), the swollen lining narrows them further, and extra mucus is made. The result: the airways become NARROWER, so LESS air can move in and out — making it hard to breathe.
Asthma has no cure. But it can be managed: an inhaler reduces the swelling and relaxes the muscles, widening the airways again. Common triggers include pollen, dust, smoke, cold air and exercise.
Keywords for Part 2
- Asthma
- A condition where the airways become inflamed and narrow, making breathing hard.
- Inflamed
- Swollen and irritated. The swollen airway lining narrows the airway.
- Inhaler
- A device that reduces swelling and widens the airways to relieve symptoms. It manages asthma — it does not cure it.
⚠ Watch out — an inhaler relieves, it does not cure
"Asthma can be cured with an inhaler" is false. There is no cure. An inhaler only manages or relieves the symptoms by widening the airways. Some people with asthma even take their inhaler before exercise to keep the airways open in advance.
What happens to the airways during an asthma attack?
- Athey widen
- Bthey become inflamed and narrow, with extra mucus
- Cthey make more cilia
- Dthey fill with oxygen
Show answer
Test yourself
8 questions · click to reveal each answer
What happens to breathing rate during exercise, and why?
It increases — the muscles need more oxygen and more carbon dioxide must be removed.What gas builds up in exercising cells?
Carbon dioxide.What does breathing rate do during sleep?
It decreases (lower than at rest).Why does breathing stay fast for a while after exercise stops?
To remove the extra carbon dioxide that built up during the exercise.What is asthma, and name two things that narrow the airways in an attack.
A condition where the airways become inflamed and narrow. Narrowing comes from the muscles contracting and extra mucus being made (plus the swollen lining).Name two asthma triggers, and explain how an inhaler helps.
Any two: pollen, dust, smoke, cold air, exercise. An inhaler reduces swelling and widens the airways.Can asthma be cured? How can you tell who is fitter from a recovery graph?
No — it can only be managed, not cured. On a recovery graph, the fitter person's breathing rate returns to normal faster.STRETCH: Suggest why exercise can be harder for someone with asthma.
Their airways are already narrowed, which limits airflow — so it is harder to get enough oxygen when active.
How smoking affects breathing
By the end of this topic you'll be able to explain the damage cigarette smoke does to every part of the gas exchange system, and why it leaves the body short of oxygen.
Part 1Damage to the airways and alveoli
Cigarette smoke is hot and contains tar, nicotine and carbon monoxide. It damages the gas exchange system at every point you've learned about.
Smoke damages the cilia — the tiny sweeping hairs in the airways. With the cilia damaged, mucus is no longer swept away, so it builds up and the body coughs to clear it: the "smoker's cough." Hot smoke and tar also damage and inflame the bronchi, causing bronchitis.
Deeper down, the folded alveoli membranes break down, leaving larger air spaces. This means a SMALLER surface area — and a smaller surface area means slower, less efficient gas exchange. On top of all this, the tar is a carcinogen — a cancer-causing chemical that can lead to mouth, throat or lung cancer.
Keywords for Part 1
- Tar
- A sticky carcinogen (cancer-causing chemical) that coats the lungs.
- Carcinogen
- A chemical that can cause cancer.
- Bronchitis
- Inflammation of the bronchi, caused here by hot smoke and tar.
Why does smoking lead to a "smoker's cough"?
- Ait widens the airways
- Bit damages the cilia, so mucus is not swept away and the body coughs to clear it
- Cit adds oxygen to the lungs
- Dit makes the alveoli bigger
Show answer
Part 2The chemicals in smoke
Three named chemicals do the harm. Tar is the sticky carcinogen that coats the lungs and causes cancer. Nicotine is the addictive chemical; it raises heart rate and blood pressure, leading to heart disease. Carbon monoxide is a gas that takes oxygen's place on red blood cells — so the blood carries LESS oxygen around the body.
So smoking harms both the lungs (less gas exchange) and the heart and blood (less oxygen carried). That double hit is why a smoker can become breathless even climbing stairs.
⚠ Watch out — carbon monoxide doesn't damage the lungs, it sabotages the blood
Carbon monoxide doesn't break down the alveoli — that's tar and heat. Instead it binds to red blood cells in place of oxygen, so even if your lungs worked perfectly, your blood would carry less oxygen. This is also why smoking is especially harmful for someone with asthma: their airways are already narrowed and inflamed, and the smoke makes both the airflow AND the oxygen-carrying worse.
How does carbon monoxide in smoke harm the body?
- Ait makes mucus
- Bit takes oxygen's place in red blood cells, so less oxygen is carried
- Cit widens the airways
- Dit cures bronchitis
Show answer
Part 3Writing the 6-mark answer
Putting it all together — how smoking damages gas exchange AND cuts the oxygen reaching your cells. Each (1) marks a scoring point.
6-mark model answer
Explain how smoking damages the gas exchange system and reduces the amount of oxygen reaching the body's cells. [6 marks]
⚠ Mark-scheme note
One mark each for: cilia damaged → cough; bronchi/alveoli damaged; smaller surface area → less gas exchange; carbon monoxide reduces oxygen carried; tar/nicotine harm. Maximum 6 marks. Notice the answer covers both halves of the question — the damage to the lungs AND the drop in oxygen carried by the blood.
Test yourself
8 questions · click to reveal each answer
Name four effects of smoking on the lungs.
Any four: damaged cilia; bronchitis; alveoli break down; smaller surface area; cancer; smoker's cough.How does smoking cause a smoker's cough?
Damaged cilia can't sweep mucus away, so mucus builds up and the body coughs to clear it.What happens to a smoker's alveoli, and how does it affect gas exchange?
The folded membranes break down, leaving larger air spaces — a smaller surface area, so slower, less efficient gas exchange.What is tar, and what can it cause?
A carcinogen (cancer-causing chemical) — it can cause mouth, throat or lung cancer.What does nicotine do? What does carbon monoxide do?
Nicotine is addictive and raises heart rate and blood pressure (heart disease). Carbon monoxide takes oxygen's place on red blood cells, so less oxygen is carried.Why does smoking increase a person's breathing rate over time?
A smaller alveoli surface area means less oxygen is absorbed, so breathing speeds up to compensate.Why is smoking especially harmful for someone with asthma?
Their airways are already narrowed and inflamed; smoke worsens this and reduces gas exchange even further.STRETCH: Explain why a smoker may get breathless climbing stairs.
A smaller surface area means less oxygen absorbed, and carbon monoxide means less oxygen carried — so the muscles get less oxygen and tire quickly.